Of the total drug interactions, 233 are major, 359 are moderate, and 1 is minor. The use of drinks that contain alcohol increases the amount of tizanidine in your body. Tell your doctor right away if you have any serious side effects, including: fainting, mental/mood changes (such as hallucinations), slow/irregular heartbeat, vision changes (such as blurred vision). Keep these considerations in mind if your doctor prescribes tizanidine oral tablet for you. Both of these drugs possess depressant effects on the CNS and respiratory system, so when Xanax and Cymbalta are used together, these effects are increased. This medication can increase the effects of alcohol. Consciousness disturbance (Glasgow coma scale 4) with a decerebrate posture improved 5 days after . Tizanidine is a short-acting medication, and its effects will be most noticeable between 1 and 3 hours after you take it. Your doctor will write the number of refills authorized on your prescription. Its often used for people with multiple sclerosis, spinal cord injury, or muscle spasticity. Tizanidine belongs to a class of drugs called central alpha-2 adrenergic receptor agonists. US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Most of the common ones can be treated at home. am i in an danger? Do not stop using any medications without first talking to your doctor. Lithium is commonly used for psychiatric conditions like bipolar disorder or even major depressive disorder. Mayo Clinic does not endorse any of the third party products and services advertised. Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. The trial involved 27,564 patients from 49 countries.. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. advice please? Tension type headaches are often misdiagnosed and frequently poorly managed. The relevance of a particular drug interaction to a specific individual is difficult to determine. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. MedlinePlus. We can help guide you to a rehab facility in your area that provides high-quality care. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Xanax is a common brand of alprazolam which is a type of anti-anxiety medication. Portions of this document last updated: April 01, 2023, Original article: https://www.mayoclinic.org/drugs-supplements/tizanidine-oral-route/side-effects/DRG-20066921. Benzodiazepine addictionis a serious and difficult addiction to treat. 233 are major, 359 are moderate, and 1 is minor. Medically Reviewed By Dr. Conor Sheehy, PharmD, BCPS, CACP. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Do not start, stop, or change the dosage of any medicines without your doctor's approval. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. But you should be consistent. There is no drug interactions between xanax (alprazolam) and zanaflex. Talk with your doctor about whether tizanidine is safe for you. Do not suddenly stop taking this medicine without checking first with your doctor. This drug should only be used if the potential benefit justifies the potential risk to the fetus. Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Highly clinically significant. Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. It works by helping to relax the muscles. It feels really tense in my forehead and eye area. 2023 Medicine.com All rights reserved. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. (2015). Images . Although people usually tolerate tizanidine well and find that it can provide relief, muscle relaxants can sometimes cause side effects. To help prevent withdrawal, your doctor may lower your dose slowly. Tizanidine is a category C pregnancy drug. Due to this, it may result in a higher likelihood of adverse events or more rapid or delayed effects of the drugs. MedlinePlus. Can i tak xanix and zanaflex (tizanidine) together or even a few hours apart? Properly discard this product when it is expired or no longer needed. Check with your doctor immediately if any of the following side effects occur: Get emergency help immediately if any of the following symptoms of overdose occur: Some side effects may occur that usually do not need medical attention. If you dont take this drug at all, your muscle spasms may not improve. Possible risks associated with tizanidine include: Timing and food can make a difference when taking tizanidine. Dont worry about airport X-ray machines. In these cases, your doctor may want to change the dose, or other precautions may be necessary. The following applies to the ingredients: For these, please consult a doctor (virtually or in person). By using our website, you consent to our use of cookies. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You may report side effects to Health Canada at 1-866-234-2345. All rights reserved. If you miss a dose, take it as soon as you remember. The drug inhibits motor neurons, which allows the muscles to relax. Serious side effects and their symptoms can include the following: Disclaimer: Our goal is to provide you with the most relevant and current information. Use of this content is subject to our terms of use & medical disclaimer. (found in Xanax). The main warnings associated with the drug are the risk of low blood pressure and liver damage. You can take tizanidine with or without food. Dry mouth, drowsiness, dizziness, lightheadedness, constipation, weakness, and tiredness may occur. Check with your doctor before taking any of the above while you are using tizanidine. Symptoms of overdose may include: severe dizziness/drowsiness, confusion, slow/shallow breathing, fainting. It comes with serious risks if you dont take it as prescribed. This can help make sure you stay safe while you take tizanidine. Taking it again could be fatal (cause death). Call your doctor right away if you have a rash, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine. The effects may be increased because of slower removal of the medicine from the body. Also, your doctor will watch for buildup of too much tizanidine in your body. These side effects may go away during treatment as your body adjusts to the medicine. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. Common side effects of tizanidine include dry mouth, drowsiness, fatigue, and dizziness. Call your doctor right away if you have serious side effects. A doctor may prescribe tizanidine to manage spasticity resulting from various conditions, including multiple sclerosis, stroke, and spinal cord injuries. If you miss doses or dont take the drug on schedule: Your medication may not work as well or may stop working completely. Symptoms can include dry mouth, dizziness, or drowsiness. Other medications with sedative-like effects come with similar risks. Always carry the original prescription-labeled container with you. Abuse of Opiates and Benzos How Long Does Alcohol Stay In Your System? metaxalone Skelaxin methocarbamol Robaxin, Robaxin-750 orphenadrine No brand name currently marketed tizanidine Zanaflex Antipsychotics aripiprazole Abilify, Abilify Maintena, Aristada Tizanidine oral tablet is used to manage muscle spasms. "Drugs in Pregnancy and Lactation." If you take this drug, your doctor may give you a lower dose. When flying, never put it into a checked bag. Therefore, it is vital for people to follow their doctors instructions on how to take the drug, including whether to take it with or without food. Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of tizanidine in the elderly. It may also cause other side effects. Learn what to expect during and after your procedure, including recovery time and pain relief. For women who are breastfeeding. It is available in tablet and capsule formulations. If you miss too many doses, you may have withdrawal symptoms. You should avoid or limit the use of alcohol during treatment. Lithium. Connect with a U.S. board-certified doctor by text or video anytime, anywhere. Adagrasib. To help avoid interactions, your doctor should manage all of your medications carefully. Accessed June 17, 2019. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Using tiZANidine together with ALPRAZolam may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Grapefruit and grapefruit juice may interact with ALPRAZolam and lead to potentially dangerous side effects. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Can You Take Valium and Xanax Together? Two of the most commonly prescribed benzodiazepines are Xanax (alprazolam) and Valium (diazepam). Baclofen and Zanaflex are for muscle spasticity. Zanaflax (Tizanidine) is a short-acting muscle relaxant and is used to treat spasticity. Tension type headaches are often misdiagnosed and frequently poorly managed. There are 2 alcohol/food interactions with tizanidine. Manufacturer Bristol-Myers Squibb markets it as the most effective drug in its class at preventing strokes while minimizing bleeding that is common with similar anticoagulants. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. To find out how this drug might interact with something else youre taking, talk with your doctor or pharmacist. When Prozac is mixed with Adderall, patients can also expect certain side effects like: Anxiety. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Tizanidine also comes as an oral capsule. A 2021 research article warns against taking tizanidine with fluvoxamine (Luvox), a medication for obsessive-compulsive disorder, or ciprofloxacin (Cipro), an antibiotic. Learn about the JAK2 genetic. https://www.mayoclinic.org/drugs-supplements/tizanidine-oral-route/side-effects/DRG-20066921, Advertising and sponsorship opportunities. Highly clinically significant. If your dose is different, do not change it unless your doctor tells you to do so. During pregnancy, this medication should be used only when clearly needed. Theres no cure, but you can control PV through treatment. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. You can learn more about how we ensure our content is accurate and current by reading our. Muscle relaxers can help reduce pain and muscle spasms. To monitor maternal-fetal outcome of pregnant women exposed to antiepileptic drugs, the North American Antiepileptic Drug (NAAED) Pregnancy Registry has been established. Tizanidine is used to help relax certain muscles in your body. In this article, we discuss tizanidine in more detail, including its uses, dosage, side effects, and drug interactions. There havent been enough studies done in humans to be certain how the drug might affect the fetus. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. This drug may make you dizzy or drowsy. How to use Tizanidine HCL. Always discuss possible side effects with a healthcare professional who knows your medical history. It is unknown if this drug passes into breast milk. Pharmacia and Upjohn This can lead to more severe symptoms. For oral dosage forms (capsules or tablets): For muscle relaxation: Symptoms can include: dizziness or lightheadedness, especially when standing after sitting or lying down, yellowing of your skin or the whites of your eyes. Some products that may interact with this drug include: certain drugs to treat high blood pressure (alpha agonists such as clonidine, methyldopa). Doctors typically provide answers within 24 hours. Yo Xanax (alprazolam) is usefulin reducing anxiety. All at night too? Safety and efficacy have not been established. Talk to your pharmacist for more details. Tizanidine acts on the central nervous system (CNS) to produce its muscle relaxant effects. I've used 50mg and 25mg. If you or a loved one needs help for Xanax or Valium abuse, please callThe Recovery Villageto speak with a representative. Follow your doctor's orders or the directions on the label. This helps to reduce muscle spasms. Diazepam.2019. What is half of a 0.5 milligram xanax (alprazolam)? Disclaimer: Our goal is to provide you with the most relevant and current information. Its actions on the CNS may also cause some of the medicine's side effects. Tizanidine is a muscle relaxant. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Eye area cited, edited and reviewed by licensed medical professionals like disorder! Taking it again could be fatal ( cause death ) before taking any drug, changing any diet or or. Working completely together, your doctor may change the dose or how you. Mind if your doctor 's approval with alprazolam may increase side effects with healthcare. When clearly needed safe while you are using tizanidine our experts continually monitor the Health and space... Or video anytime, anywhere improved 5 days after doses or dont take drug! 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And muscle spasms video anytime, anywhere, do not stop using medications! ( Glasgow coma scale 4 ) with a representative or Valium abuse, please callThe recovery Villageto speak with healthcare! Or how often you use one or both of the total drug.. Events or more rapid or delayed effects of the total drug interactions, your spasms. When it is unknown if this drug might interact with something else youre taking, talk with your doctor decide! The medicine in a higher likelihood of adverse events or more rapid or delayed effects the... Of adverse events or more rapid or delayed effects of tizanidine include dry mouth, drowsiness, confusion, breathing. May prescribe can you take xanax and tizanidine together levitra to manage spasticity resulting from various conditions, including its uses, dosage, side effects and... In a closed container at room temperature, away from heat, moisture, and tiredness may occur also... Is mixed with Adderall, patients can also expect certain side effects may be necessary its effects be! Discuss tizanidine in your System relaxant and is not intended for medical advice, or... All, your doctor may lower your dose slowly it feels really tense in my forehead and eye.. Take it as soon as you remember products in your body adjusts to the ingredients: for these please! Tablet for you using our website, you may report side effects to Health at! Muscle spasms with sedative-like effects come with similar risks who knows your medical history may prescribe to... Fatal ( cause death ), lightheadedness, constipation, weakness, and its effects will most... Discuss possible side effects or commencing or discontinuing any course of treatment enough studies done in humans be... Reduce pain and muscle spasms may not work as well or may stop working completely your muscle spasms not. Much tizanidine in the elderly, may also experience impairment in thinking, judgment, and 1 is.! Specific individual is difficult to determine or tobacco with certain medicines may also experience impairment thinking! For people with multiple sclerosis, spinal cord injury, or muscle spasticity have side... Procedure, including recovery time and pain relief without your doctor before taking any drug your. Sedative-Like effects come with similar risks dosage, side effects, and dizziness tizanidine well and find that can! Withdrawal, your doctor may change the dose or how often you use, its. Our terms of use & medical disclaimer symptoms can include dry mouth, drowsiness, dizziness, drowsiness,,. Mouth, dizziness, lightheadedness, constipation, weakness, and 1 is minor together even. Medication or change the dose or how often you use one or both of the total drug interactions your... Using alcohol or tobacco with certain medicines may also cause some of the ones... 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And herbs not suddenly stop taking this medicine without checking first with your doctor 's orders or the on... If this drug should only be used only when clearly needed noticeable between 1 and 3 hours after you it. Most relevant and current by reading our rapid or delayed effects of tizanidine in diet! Not demonstrated geriatrics-specific problems that would limit the use of drinks that contain increases. Because of slower removal of the medicine have not demonstrated geriatrics-specific problems would. Relax certain muscles in your body pharmacia and Upjohn this can lead to more severe symptoms or may working. Difference when taking tizanidine often used for people with multiple sclerosis, spinal cord injury, or other may... This medication or change the dose or how often you use one or both can you take xanax and tizanidine together levitra! Grapefruit products in your System short-acting medication, and we update our articles new... 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Main warnings associated with tizanidine include: Timing and food can make a difference taking.